Article
Resistance to adefovir dipivoxil in lamivudine resistant chronic hepatitis B patients treated with adefovir dipivoxil.
Gut - 1 Oct 2006
Yeon J E, Yoo W, Hong S P, Chang Y J, Yu S K, Kim J H, Seo Y S, Chung H J, Moon M S, Kim S-O, Byun K S, Lee C H
Abstract excerpt
BACKGROUND: Adefovir dipivoxil (ADV) is a potent nucleotide analogue against both the wild-type and lamivudine (LMV) resistant hepatitis B virus (HBV). The cumulative incidence of ADV resistant mutations in the nucleoside/-tide treatment naive chronic hepatitis B patient (CHB) at weeks 48, 96, and 144 was 0, 0.8-3%, and approximately 5.9%, respectively. AIMS: The aim of this study was to characterise the...
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