Article
Efficacy of adefovir dipivoxil in the treatment of lamivudine-resistant hepatitis B virus genotype C infection.
Liver international : official journal of the International Association for the Study of the Liver - 1 Feb 2007
Kim Do Young, Kim Hong Jeoung, Lee Chun Kyon, Suh Jeong Hun, Kim Dong Hwan, Cho Yong Suk, Won Sun Young, Park Byung Kyu, Park In Suh
Abstract excerpt
BACKGROUND AND AIMS: Adefovir dipivoxil (ADV) is a nucleotide analogue that is known to be effective for lamivudine-resistant hepatitis B virus (HBV) mutants as well as wild-type HBV. The aim of this study is to assess the efficacy of ADV against lamivudine-resistant genotype C HBV mutants. METHODS: Thirty-five patients with breakthrough hepatitis due to lamivudine-resistant HBV received ADV 10 mg daily with...
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