Article
[The efficacy of adefovir dipivoxil monotherapy and the incidence of genotypic resistance to adefovir dipivoxil in patients with lamivudine-resistant chronic hepatitis B infection].
The Korean journal of hepatology - 1 Dec 2008
Moon Jae Hyeon, Cho Mong, Yoon Ki Tae, Bae Jung Ho, Heo Jeong, Kim Gwang Ha, Kang Dae Hwan, Song Geun Am
Abstract excerpt
BACKGROUND/AIMS: Adefovir dipivoxil (ADV) is a nucleotide analogue that inhibits wild-type hepatitis B virus (HBV) and lamivudine (LMV)-resistant HBV mutants. The aim of this study was to elucidate the efficacy of ADV monotherapy and the incidence of genotypic resistance to ADV in patients with LMV-resistant chronic HBV infection. METHODS: This study involved 124 patients with chronic HBV infection who had...
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