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Article

Adefovir dipivoxil is effective for the treatment of cirrhotic patients with lamivudine failure.

Liver international : official journal of the International Association for the Study of the Liver - 1 Mar 2009

Zoulim Fabien, Parvaz Parviz, Marcellin Patrick, Zarski Jean-Pierre, Beaugrand Michel, Benhamou Yves, Bailly François, Maynard Marianne, Trepo Christian, Trylesinski Aldo, Monchecourt Françoise

Abstract excerpt

BACKGROUND/AIMS: Data on the efficacy of adefovir dipivoxil (ADV) in elderly and cirrhotic patients with lamivudine-resistant (LAM-R) chronic hepatitis B are scarce. This retrospective cohort study evaluated the safety and efficacy of ADV in this specific patient population. METHODS: Sixty-eight cirrhotic LAM-R patients, of whom 19 (27.9%) were elderly (>or=65 years of age) and nine had severe disease (two...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18795900
DOI: 10.1111/j.1478-3231.2008.01867.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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