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Article

The influence of YMDD mutation patterns on clinical outcomes in patients with adefovir add-on lamivudine combination treatment.

Liver international : official journal of the International Association for the Study of the Liver - 1 Feb 2012

Kim Hong J, Park Jung H, Park Dong I, Cho Yong K, Sohn Chong I, Jeon Woo K, Kim Byung I

Abstract excerpt

BACKGROUND/AIM: The aim of this study was to assess the patterns of lamivudine (LAM)-resistant mutations and the influence on biochemical and virological responses to adefovir (ADV) add-on LAM combination therapy in patients with LAM-resistant chronic hepatitis B (CHB). METHODS: Seventy-eight CHB patients with confirmed genotypic resistance to LAM, who initiated ADV add-on LAM combination treatment, were enrolled...

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Identifiers

PMID: 22098177
DOI: 10.1111/j.1478-3231.2011.02647.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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