Article
Adefovir dipivoxil added to ongoing lamivudine in chronic hepatitis B with YMDD mutant hepatitis B virus.
Gastroenterology - 1 Jan 2004
Perrillo Robert, Hann Hie-Won, Mutimer David, Willems Bernard, Leung Nancy, Lee William M, Moorat Alison, Gardner Stephen, Woessner Mary, Bourne Eric, Brosgart Carol L, Schiff Eugene
Abstract excerpt
BACKGROUND AND AIMS: Prolonged lamivudine therapy is associated with treatment-resistant YMDD mutant hepatitis B virus (HBV). We evaluated the efficacy and safety of adding adefovir dipivoxil to lamivudine in 135 patients with chronic hepatitis B (CHB) and YMDD mutant HBV. METHODS: Ninety-five pa...
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