Article
The battle of two genomes: genetics of bacterial host/pathogen interactions in mice.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Apr 2001
Lengeling A, Pfeffer K, Balling R
Abstract excerpt
Genetic factors strongly determine the outcome of infectious diseases caused by various pathogens. The molecular mechanisms of resistance and susceptibility in humans, however, remains largely unknown. Complex interactions of multiple genes that control the host response to a pathogen further complicate the picture. Animal models have a tremendous potential to dissect the complex genetic system of host-pathogen...
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