Article
Association analysis of NOTCH 4 polymorphisms with schizophrenia among two independent family based samples.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 15 Nov 2004
Prasad S, Chowdari K V, Wood J, Bhatia T, Deshpande S N, Nimgaonkar V L, Thelma B K
Abstract excerpt
The present study investigated polymorphisms of the NOTCH 4 gene in two independent samples from India and USA, consisting of patients with schizophrenia and their parents (n = 182, and n = 148 'trios,' respectively). Five DNA markers, namely (GAAG)(n), (TAA)(n), SNP1, SNP2, and (CTG)(n) were evaluated. Transmission distortion, consistent with a modest association was detected among both samples. Additional...
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