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Article

p27(Kip1)-stathmin interaction influences sarcoma cell migration and invasion.

Cancer cell - 1 Jan 2005

Baldassarre Gustavo, Belletti Barbara, Nicoloso Milena S, Schiappacassi Monica, Vecchione Andrea, Spessotto Paola, Morrione Andrea, Canzonieri Vincenzo, Colombatti Alfonso

Abstract excerpt

Emerging evidences suggest that cyclin-dependent kinase inhibitors (CKIs) can regulate cellular functions other than cell cycle progression, such as differentiation and migration. Here, we report that cytoplasmic expression of p27(kip1) affects microtubule (MT) stability following cell adhesion on extracellular matrix (ECM) constituents. This p27(kip1) activity is due to its ability to bind and impair the...

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Identifiers

PMID: 15652749
DOI: 10.1016/j.ccr.2004.11.025

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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