Article
Stathmin activity influences sarcoma cell shape, motility, and metastatic potential.
Molecular biology of the cell - 1 May 2008
Belletti Barbara, Nicoloso Milena S, Schiappacassi Monica, Berton Stefania, Lovat Francesca, Wolf Katarina, Canzonieri Vincenzo, D'Andrea Sara, Zucchetto Antonella, Friedl Peter, Colombatti Alfonso, Baldassarre Gustavo
Abstract excerpt
The balanced activity of microtubule-stabilizing and -destabilizing proteins determines the extent of microtubule dynamics, which is implicated in many cellular processes, including adhesion, migration, and morphology. Among the destabilizing proteins, stathmin is overexpressed in different human malignancies and has been recently linked to the regulation of cell motility. The observation that stathmin was...
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