Article
Genetic characterization of p27(kip1) and stathmin in controlling cell proliferation in vivo.
Cell cycle (Georgetown, Tex.) - 1 Jan 2014
Berton Stefania, Pellizzari Ilenia, Fabris Linda, D'Andrea Sara, Segatto Ilenia, Canzonieri Vincenzo, Marconi Daniela, Schiappacassi Monica, Benevol Sara, Gattei Valter, Colombatti Alfonso, Belletti Barbara, Baldassarre Gustavo
Abstract excerpt
The CDK inhibitor p27(kip1) is a critical regulator of cell cycle progression, but the mechanisms by which p27(kip1) controls cell proliferation in vivo are still not fully elucidated. We recently demonstrated that the microtubule destabilizing protein stathmin is a relevant p27(kip1) binding partner. To get more insights into the in vivo significance of this interaction, we generated p27(kip1) and stathmin...
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