Article
The function of p27 KIP1 during tumor development.
Experimental & molecular medicine - 30 Nov 2009
Lee Jinhwa, Kim Sung Soo
Abstract excerpt
Timely cell cycle regulation is conducted by sequential activation of a family of serine-threonine kinases called cycle dependent kinases (CDKs). Tight CDK regulation involves cyclin dependent kinase inhibitors (CKIs) which ensure the correct timing of CDK activation in different phases of the cell cycle. One CKI of importance is p27(KIP1). The regulation and cellular localization of p27(KIP1) can result in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
