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Article

The importance of mutation, then and now: studies with yeast cytochrome c.

Mutation research - 1 Jan 2005

Sherman Fred

Abstract excerpt

The development of a genetic system based on the CYC1 gene was initiated over 40 years ago, primarily because of the anticipated ease of sequencing of the corresponding encoded protein, iso-1-cytochrome c from Saccharomyces cerevisiae. The success of the iso-cytochrome c system was dependent on the early development of methods for detecting and selecting cyc1 defective mutants and CYC1 functional revertants, and...

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Source

Identifiers

PMID: 15652223
DOI: 10.1016/j.mrrev.2004.07.001

Genes

CYC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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