Article
A mutation in the gene encoding cytochrome c1 leads to a decreased ROS content and to a long-lived phenotype in the filamentous fungus Podospora anserina.
Fungal genetics and biology : FG & B - 1 Jul 2007
Sellem Carole H, Marsy Sophie, Boivin Antoine, Lemaire Claire, Sainsard-Chanet Annie
Abstract excerpt
We present here the properties of a complex III loss-of-function mutant of the filamentous fungus Podospora anserina. The mutation corresponds to a single substitution in the second intron of the gene cyc1 encoding cytochrome c(1), leading to a splicing defect. The cyc1-1 mutant is long-lived, exhibits a defect in ascospore pigmentation, has a reduced growth rate and a reduced ROS production associated with a...
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