Article
Mutational analysis of the Saccharomyces cerevisiae cytochrome c oxidase assembly protein Cox11p.
Eukaryotic cell - 1 Mar 2006
Banting Graham S, Glerum D Moira
Abstract excerpt
Cox11p is an integral protein of the inner mitochondrial membrane that is essential for cytochrome c oxidase assembly. The bulk of the protein is located in the intermembrane space and displays high levels of evolutionary conservation. We have analyzed a collection of site-directed and random cox11 mutants in an effort to further define essential portions of the molecule. Of the alleles studied, more than half...
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