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Article

Tissue factor and thrombosis models.

Arteriosclerosis, thrombosis, and vascular biology - 1 May 2010

Kretz Colin A, Vaezzadeh Nima, Gross Peter L

Abstract excerpt

Mouse models of thrombosis have extended our understanding of the role of tissue factor (TF) in thrombogenesis. Because tissue factor deficiency is embryonic lethal in mice, inventive genetic models are required to probe the role of TF in thrombosis. TF is expressed by different cell types, including vascular smooth muscle cells, cardiomyocytes, fibroblasts, and monocytes. Platelets and endothelial cells also...

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Identifiers

PMID: 20393156
DOI: 10.1161/ATVBAHA.108.177477

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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