Article
CYP2D6 and CYP1A1 mutations in the Turkish population.
Cell biochemistry and function - 1 Jan 2000
Aydin Muge, Hatirnaz Ozden, Erensoy Nevin, Ozbek Ugur
Abstract excerpt
Drugs and carcinogens are substrates of a group of metabolic enzymes including cytochrome p450 enzymes and gluthatione S-transferases. Many of the genes encoding these enzymes exhibit functional polymorphisms that contribute individual cancer susceptibility and drug response. Molecular studies based on these polymorphic enzymes also explain the aetiology of cancer and therapeutic management in clinics. We...
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