Article
CYP2D6, CYP2E1 Gene Polymorphisms and Gastrointestinal Cancer Risk in Rural Maharashtra: A Hospital Based Case-Control Study.
Asian Pacific journal of cancer prevention : APJCP - 1 Sept 2024
Datkhile Kailas D, More Ashwini L, Patil Madhavi N, Gudur Rashmi A, Gudur Anand K
Abstract excerpt
BACKGROUND: Cytochrome P450 (CYP) is a family phase I metabolizing enzymes important in xenobiotics metabolism. Genetic polymorphisms of CYPs have been comprehensively studied for their association with a range of diseases including cancer risk. In this study we assessed single nucleotide polymorphism (SNP) CYP2D6 and CYP2E1 genes and their role in gastrointestinal (GI) cancer susceptibility in the rural...
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