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Article

The frequencies of mutated alleles of CYP2D6 gene in a Turkish population.

Forensic science international - 10 Oct 2012

Serin A, Canan H, Alper B, Gulmen M

Abstract excerpt

Allele and genotype frequency distribution of CYP2D6*3, *4, *5, *6 and *10 variants were analyzed in blood samples of 100 unrelated healthy individuals by Real-Time PCR. The allele frequencies of CYP2D6*3(A2549del), *4(G1846A), *6(T1707del) and *10(C100T) were 1%, 10%, 2.5% and 14.5% respectively, while allele frequency of CYP2D6*5 was 3% of the subjects tested. Extensive, poor and intermediate metabolizer (EM,...

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Identifiers

PMID: 22910059
DOI: 10.1016/j.forsciint.2012.07.012

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