Article
[Effect of estradiol on food intake, glucose and fat metabolism in mice C57BL/6J with mutation yellow at the agouti locus].
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova - 1 May 2012
Iakovleva T V, Makarova E N, Kazantseva A Iu, Bazhan N M
Abstract excerpt
Mutation yellow at the agouti locus in mice (A(y)/a-mice) causes the increase of food intake and development of obesity and type 2 diabetes. In A(y)/a-females the disturbances of glucose and fat metabolisms occur after puberty. We have assumed that the mutation yellow violates the regulatory effect of estradiol on glucose and fat metabolism in mice. We investigated the effects of ovariectomy and estradiol...
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