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An embryonic poly(A)-binding protein (ePAB) is expressed in mouse oocytes and early preimplantation embryos

3 Jan 2005

Abstract excerpt

Gene expression during oocyte maturation, fertilization, and early embryo development until zygotic gene activation is regulated mainly by translational activation of maternally derived mRNAs. This process requires the presence of a poly(A)-binding protein. However, the cytoplasmic somatic cell poly(A)-binding protein (PABP1) is not expressed until later in embryogenesis. We recently identified an embryonic...

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PMID: 15630085
DOI: 10.1073/pnas.0408378102

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