Article
Alternative splicing of the mouse embryonic poly(A) binding protein (Epab) mRNA is regulated by an exonic splicing enhancer: a model for post-transcriptional control of gene expression in the oocyte.
Molecular human reproduction - 1 Jul 2008
Seli Emre, Yaba Aylin, Guzeloglu-Kayisli Ozlem, Lalioti Maria D
Abstract excerpt
Embryonic poly(A) binding protein (EPAB), expressed in oocytes and early embryos, binds and stabilizes maternal mRNAs, and mediates initiation of their translation. We identified an alternatively spliced form of Epab lacking exon 10 (c.Ex10del) and investigated the regulation of Epab mRNA alternative splicing as a model for alternative splicing in oocytes and early preimplantation embryos. Specifically, we...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.