Article
Uveal and Cutaneous Melanoma: Shared Expression Characteristics of Melanoma-Associated Antigens
28 Dec 2004
Abstract excerpt
PURPOSE: Downregulation of melanoma-associated antigens (MAAs), against which natural cytolytic T lymphocytes (CTLs) exist in humans, is one of the mechanisms that aids in evasion of immune surveillance. In view of putative re-expression strategies for MAAs during immunotherapy, this study was conducted to investigate MAA silencing in malignant melanoma. METHODS: The expression of the MAA Melan-A/MART-1 was...
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