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Cancer testis antigens in human melanoma stem cells: Expression, distribution, and methylation status

18 Jan 2008

Abstract excerpt

Neoplastic populations with stem cell potential have been most recently identified in human cutaneous melanoma, and initially characterized for their phenotypic profile. Being melanoma stem cells (MSC) the most desirable target of therapeutic intervention, we asked whether they express the epigenetically-regulated cancer testis antigens (CTA) on which melanoma immunotherapy is increasingly focusing. Reverse...

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PMID: 18205182
DOI: 10.1002/jcp.21380

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