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Article

How to Make Immunotherapy an Effective Therapeutic Choice for Uveal Melanoma

23 Apr 2021

Abstract excerpt

Uveal melanoma (UM), though a rare form of melanoma, is the most common intraocular tumor in adults. Conventional therapies of primary tumors lead to an excellent local control, but 50% of patients develop metastases, in most cases with lethal outcome. Somatic driver mutations that act on the MAP-kinase pathway have been identified, yet targeted therapies show little efficacy in the clinics. No drugs are...

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PMID: 33922591
DOI: 10.3390/cancers13092043

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