Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CpG island methylation profiling in human melanoma cell lines.

Melanoma research - 1 Jun 2009

Tellez Carmen S, Shen Lanlan, Estécio Marcos R H, Jelinek Jaroslav, Gershenwald Jeffrey E, Issa Jean-Pierre J

Abstract excerpt

A better understanding of key molecular changes during the pathogenesis of melanoma could impact strategies to reduce mortality from this cancer. Two epigenetic events involved in the pathogenesis of cancer are hypermethylation of tumor-suppressor gene promoters associated with transcriptional repression and hypomethylation associated with gene reexpression and genomic instability. We analyzed 16 melanoma cell...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Line, Tumor
Share to CpG Islands
Share to DNA Methylation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Epigenesis, Genetic

Share to Gene Expression Profiling

Share to Gene Expression Regulation, Neoplastic

Share to Melanoma

Share to Skin Neoplasms

Source

Identifiers

PMID: 19441164
DOI: 10.1097/cmr.0b013e32832b274e

Genes

BRAF
NRAS
CDH13
HAND1
MAGEA1
MGMT
MLH1
OLIG2
PAX2
PAX7
PGR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CpG island methylation profiling in human melanoma cell lines.PMID 19441164Read ↗

Epigenetics in Human MelanomaSemantic proximity Read ↗

Update on melanoma epigeneticsSemantic proximity Read ↗

DNA methylation aberrancy is a reliable prognostic tool in uveal melanomaSemantic proximity Read ↗

Genome-wide DNA methylation and RNA expression differences correlate with invasiveness in melanoma cell lines.Semantic proximity Read ↗

LINE-1 hypomethylation and mutational status in cutaneous melanomas.Semantic proximity Read ↗

LINE-1 hypermethylation in peripheral blood of cutaneous melanoma patients is associated with metastasis.Semantic proximity Read ↗

Methylation Markers in Cutaneous Melanoma: Unravelling the Potential Utility of Their Tracking by Liquid BiopsySemantic proximity Read ↗

Targeting DNA Methylation and EZH2 Activity to Overcome Melanoma Resistance to ImmunotherapySemantic proximity Read ↗

Integrated multi-omics profiling reveals the role of the DNA methylation landscape in shaping biological heterogeneity and clinical behaviour of metastatic melanomaSemantic proximity Read ↗

Methylation levels of the "long interspersed nucleotide element-1" repetitive sequences predict survival of melanoma patientsSemantic proximity Read ↗

Histone variants and melanoma: facts and hypotheses.Semantic proximity Read ↗

Aberrant DNA methylation is associated with aggressive clinicopathological features and poor survival in cutaneous melanoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.