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Article

Melanoma antigen recognition by tumour-infiltrating T lymphocytes (TIL): effect of differential expression of melan-A/MART-1.

Clinical and experimental immunology - 1 Jan 2000

Ramirez-Montagut T, Andrews D M, Ihara A, Pervaiz S, Pandolfi F, Van Den Elsen P J, Waitkus R, Boyle L A, Hishii M, Kurnick J T

Abstract excerpt

We have isolated, from an individual patient with metastatic melanoma, a series of eight TIL clones capable of lysing autologous melanoma cell targets. Six of the eight clones expressed TCRAV2S1 and lysed targets expressing HLA-A2 and the Melan-A/MART-1 peptide: AAGIGILTV. Polymerase chain reaction-single stranded conformational polymorphism (PCR-SSCP) analysis showed that the Melan-A/MART-1-specific clones were...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Lymphocytes, Tumor-Infiltrating

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Share to Polymorphism, Single-Stranded Conformational

Share to Receptors, Antigen, T-Cell, alpha-beta

Source

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Identifiers

PMID: 10606959
DOI: 10.1046/j.1365-2249.2000.01089.x
PMCID: PMC1905547

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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