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Article

Cancer Cell Phenotype Plasticity as a Driver of Immune Escape in Melanoma.

Frontiers in immunology - 1 Jan 2022

Benboubker Valentin, Boivin Félix, Dalle Stéphane, Caramel Julie

Abstract excerpt

Immunotherapies blocking negative immune checkpoints are now approved for the treatment of a growing number of cancers. However, even in metastatic melanoma, where sustained responses are observed, a significant number of patients still do not respond or display resistance. Increasing evidence indicates that non-genetic cancer cell-intrinsic alterations play a key role in resistance to therapies and immune...

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Identifiers

PMID: 35432344
DOI: 10.3389/fimmu.2022.873116
PMCID: PMC9012258

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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