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Article

Lack of association of IL-12 p40 gene polymorphism with peptic ulcer disease.

Human immunology - 1 Jan 2005

García-González María A, Lanas Angel, Wu Jing, Benito Rafael, Santolaria Santos, Crusius Bart, Peña Salvador

Abstract excerpt

Interleukin 12 (IL-12) is a proinflammatory cytokine composed by two chains, p40 and p35, that plays a key role in the promotion of a Th1 immune response in the gastrointestinal mucosa. An enhanced expression of IL-12 mRNA in gastric mucosa has been reported in individuals infected by Helicobacter pylori. The aim of our study was to assess whether a functional polymorphism located at position 1188 (A-->C) of the...

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Identifiers

PMID: 15620465
DOI: 10.1016/j.humimm.2004.10.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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