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Article

Assessment of TNFA polymorphisms at positions -857 and -863 in Polish peptic ulcer patients.

Advances in medical sciences - 1 Mar 2016

Sałagacka-Kubiak Aleksandra, Zebrowska Marta, Jeleń Agnieszka, Mirowski Marek, Balcerczak Ewa

Abstract excerpt

PURPOSE: Peptic ulceration connected with chronic inflammation in gastrointestinal mucosa could be induced by Helicobacter pylori infection. Tumor necrosis factor alpha (TNF-α) encoded by TNFA gene is a key mediator in the inflammation process. There are several polymorphisms in the promoter of TNFA influencing its transcriptional activity. -857C>T (rs1799724) and -863C>A (rs1800630) substitutions may be...

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PMID: 26774268
DOI: 10.1016/j.advms.2015.12.002

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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