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Article

Levels of interleukin-18 are markedly increased in Helicobacter pylori-infected gastric mucosa among patients with specific IL18 genotypes.

The Journal of infectious diseases - 15 Jun 2008

Sakai Kyoko, Kita Masakazu, Sawai Naoki, Shiomi Satoshi, Sumida Yoshio, Kanemasa Kazuyuki, Mitsufuji Shoji, Imanishi Jiro, Yamaoka Yoshio

Abstract excerpt

BACKGROUND: The cellular immune response in gastric mucosa infected with Helicobacter pylori is proposed to be predominantly of the T helper cell type 1 type. METHODS: Interleukin (IL)-18, IL-12, and interferon (IFN)-gamma levels were measured in gastric mucosal biopsy specimens by reverse-transcription polymerase chain reaction (PCR) and by enzyme-linked immunosorbent assay; IL18 polymorphisms were determined by...

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Identifiers

PMID: 18442334
DOI: 10.1086/588196
PMCID: PMC2833342

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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