Article
Single nucleotide polymorphism in the interleukin 12B gene is associated with risk for breast cancer development.
Scandinavian journal of immunology - 1 Sept 2012
Kaarvatn M H, Vrbanec J, Kulic A, Knezevic J, Petricevic B, Balen S, Vrbanec D, Dembic Z
Abstract excerpt
We analysed the association of a single nucleotide polymorphism (SNP) in the gene encoding the IL-12 subunit p40 (IL12B, rs3212227, A>C) with breast cancer. The SNPs allelic and genotypic frequencies were compared between patients (n = 191) and healthy (n = 194) women in a case-control study from Croatia. The major allele (A) was associated with susceptibility to breast cancer (P = 0.003; OR = 1.67; 95% CI:...
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