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Article

The polymorphic IL-1B and IL-1RN genes in the aetiopathogenesis of peptic ulcer.

Clinical and experimental immunology - 1 Sept 2001

Garcia-Gonzalez M A, Lanas A, Santolaria S, Crusius J B, Serrano M T, Peña A S

Abstract excerpt

Besides environmental factors, the genetic background of an individual may contribute to the development and final outcome of peptic ulcer disease. Interleukin-1beta (IL-1beta) and the interleukin-1 receptor antagonist (IL-1ra) are cytokines that play a key role in modulating the inflammatory response in the gastrointestinal mucosa. This study aimed to investigate whether polymorphisms in the IL-1B and IL-RN...

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Source

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Identifiers

PMID: 11531943
DOI: 10.1046/j.1365-2249.2001.01593.x
PMCID: PMC1906147

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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