Article
No allelic variant associations of the IL-1 and TNF gene polymorphisms in the susceptibility to duodenal ulcer disease.
International journal of immunogenetics - 1 Oct 2005
Garcia-Gonzalez M A, Savelkoul P H M, Benito R, Santolaria S, Crusius J B A, Peña A S, Lanas A
Abstract excerpt
Recent studies have reported the association of a pro-inflammatory profile of genetic polymorphisms in IL-1B, IL-1RN, TNF-A, and IL-10 genes with an increased risk of non-cardia gastric cancer. Because gastric cancer and duodenal ulcer are mutually exclusive outcomes of Helicobacter pylori infection, we aimed to investigate possible allelic variant associations of several functional polymorphisms in the IL-1B,...
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