Article
Human leukocyte antigen-E alleles and expression in patients with serous ovarian cancer.
Cancer science - 1 May 2015
Zheng Hui, Lu Renquan, Xie Suhong, Wen Xuemei, Wang Hongling, Gao Xiang, Guo Lin
Abstract excerpt
Human leukocyte antigen-E (HLA-E) is one of the most extensively studied non-classical MHC class I molecules that is almost non-polymorphic. Only two alleles (HLA-E*0101 and HLA-E*0103) are found in worldwide populations, and suggested to be functional differences between these variants. The HLA-E molecule can contribute to the escape of cancer cells from host immune surveillance. However, it is still unknown...
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