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Article

Analysis of HLA-E expression in human tumors.

Immunogenetics - 1 Feb 2003

Marín Rosario, Ruiz-Cabello Francisco, Pedrinaci Susana, Méndez Rosa, Jiménez Pilar, Geraghty Daniel E, Garrido Federico

Abstract excerpt

Downregulation of MHC class Ia molecule expression is a widespread mechanism used by tumor cells to escape antitumor T-cell-mediated immune responses. However, it is not known why NK cells cannot lyse these MHC class-Ia-deficient tumor targets. Tumors must select additional routes of escape from NK cells. An attractive hypothesis is that the aberrant expression of nonclassical HLA class Ia molecules in tumors...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12618909
DOI: 10.1007/s00251-002-0526-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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