Article
The psychogenetically selected Roman rat lines differ in the susceptibility to develop amphetamine sensitization.
Behavioural brain research - 10 Feb 2005
Corda Maria G, Piras Giovanna, Lecca Daniele, Fernández-Teruel Alberto, Driscoll Peter, Giorgi Osvaldo
Abstract excerpt
The mesolimbic dopamine system is considered to play a pivotal role in the locomotor activation produced by psychostimulants and in the augmentation of this effect observed upon repeated drug administration, a process denominated behavioral sensitization. The selective breeding of Roman high- (RHA) and low-avoidance (RLA) rats, respectively, for rapid versus poor active avoidance acquisition has resulted in two...
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