Article
Distinct phenotypes of spontaneous activity and induction of amphetamine sensitization in inbred Roman high- and low-avoidance rats: Vulnerability and protection.
Neuroscience letters - 23 Apr 2018
Giménez-Llort Lydia, Guitart-Masip Marc, Tobeña Adolf, Fernández-Teruel Albert, Johansson Björn
Abstract excerpt
The psychogenetically selected Roman high- (RHA) and low-avoidance (RLA) rats are being proposed as a valuable animal model of individual vulnerability to the two distinct neurobiological mechanisms of behavioral sensitization to psychostimulants, namely induction and expression. Most hallmarks of their divergent phenotypes are also found in the inbred RHA (RHA-I) and RLA (RLA-I) strains. For instance, they...
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