Inbred rat strain comparisons indicate different sites of action for cocaine and amphetamine locomotor stimulant effects.

doi:10.1007/BF02245649

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Article

Inbred rat strain comparisons indicate different sites of action for cocaine and amphetamine locomotor stimulant effects.

Psychopharmacology - 1 Jan 1991

George F R, Porrino L J, Ritz M C, Goldberg S R

Abstract excerpt

Cocaine and amphetamine produce several behavioral effects, most notably locomotor stimulation. Biochemically, evidence suggests specific involvement of dopaminergic systems, although not necessarily identical sites, in mediating cocaine- and amphetamine-induced locomotor stimulation. This study examined the effects of cocaine or amphetamine on locomotor activity in rats from the ACI, F344, LEW and NBR inbred...

Topics

Amphetamine
Animals
Cocaine
Corpus Striatum
Dose-Response Relationship, Drug
Genotype
In Vitro Techniques
Male
Mazindol
Motor Activity
Rats
Rats, Inbred ACI

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Rats, Inbred F344

Rats, Inbred Lew

Rats, Inbred Strains

Receptors, Dopamine

Receptors, Dopamine D1

Receptors, Dopamine D2

Source

Open in PubMed

Identifiers

PMID: 1838200
DOI: 10.1007/BF02245649

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1838200-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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