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Article

CCR6 expression defines regulatory effector/memory-like cells within the CD25(+)CD4+ T-cell subset.

Blood - 1 Apr 2005

Kleinewietfeld Markus, Puentes Fabiola, Borsellino Giovanna, Battistini Luca, Rötzschke Olaf, Falk Kirsten

Abstract excerpt

Regulatory CD25(+)CD4+ T cells (Treg cells) are a central element of peripheral tolerance. Little is known, however, about phenotypic and functional characteristics of these cells with regard to memory. In this study we show that the chemokine receptor CCR6 is expressed on a distinct subset of mouse Treg cells. Similar to their CD25- counterparts, CCR6+ Treg cells exhibit markers of activation, memory, and...

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Source

Identifiers

PMID: 15613550
DOI: 10.1182/blood-2004-07-2505

Genes

CCR6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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