Article
CCR6 recruits regulatory T cells and Th17 cells to the kidney in glomerulonephritis.
Journal of the American Society of Nephrology : JASN - 1 Jun 2010
Turner Jan-Eric, Paust Hans-Joachim, Steinmetz Oliver M, Peters Anett, Riedel Jan-Hendrik, Erhardt Annette, Wegscheid Claudia, Velden Joachim, Fehr Susanne, Mittrücker Hans-Willi, Tiegs Gisa, Stahl Rolf A K, Panzer Ulf
Abstract excerpt
T cells recruited to the kidney contribute to tissue damage in crescentic and proliferative glomerulonephritides. Chemokines and their receptors regulate T cell trafficking, but the expression profile and functional importance of chemokine receptors for renal CD4+ T cell subsets are incompletely understood. In this study, we observed that renal FoxP3+CD4+ regulatory T cells (Tregs) and IL-17-producing CD4+ T...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
