Article
Gln-tRNAGln formation from Glu-tRNAGln requires cooperation of an asparaginase and a Glu-tRNAGln kinase.
The Journal of biological chemistry - 4 Mar 2005
Feng Liang, Sheppard Kelly, Tumbula-Hansen Debra, Söll Dieter
Abstract excerpt
Gln-tRNA(Gln) is synthesized from Glu-tRNA(Gln) in most microorganisms by a tRNA-dependent amidotransferase in a reaction requiring ATP and an amide donor such as glutamine. GatDE is a heterodimeric amidotransferase that is ubiquitous in Archaea. GatD resembles bacterial asparaginases and is expected to function in amide donor hydrolysis. We show here that Methanothermobacter thermautotrophicus GatD acts as a...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
