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Article

Divergent anticodon recognition in contrasting glutamyl-tRNA synthetases.

Journal of molecular biology - 10 Dec 2004

Lee Joohee, Hendrickson Tamara L

Abstract excerpt

The pathogenic bacterium Helicobacter pylori utilizes two essential glutamyl-tRNA synthetases (GluRS1 and GluRS2). These two enzymes are closely related in evolution and yet they aminoacylate contrasting tRNAs. GluRS1 is a canonical discriminating GluRS (D-GluRS) that biosynthesizes Glu-tRNA(Glu) and cannot make Glu-tRNA(Gln). In contrast, GluRS2 is non-canonical as it is only essential for the production of...

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Identifiers

PMID: 15561136
DOI: 10.1016/j.jmb.2004.10.013
PMCID: PMC2897014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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