Article
Glycyl-tRNA synthetase from Thermus thermophilus--wide structural divergence with other prokaryotic glycyl-tRNA synthetases and functional inter-relation with prokaryotic and eukaryotic glycylation systems.
European journal of biochemistry - 1 Feb 1998
Mazauric M H, Keith G, Logan D, Kreutzer R, Giegé R, Kern D
Abstract excerpt
The tRNA glycylation system is amongst the most complex aminoacylation systems since neither the oligomeric structure of the enzymes nor the discriminator base in tRNAs are conserved in the phylae. To understand better this structural diversity and its functional consequences, the prokaryotic gly...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Cloning, Molecular
- Consensus Sequence
- DNA Primers
- Genetic Variation
- Glycine-tRNA Ligase
- Humans
- Mammals
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Polymerase Chain Reaction
- Prokaryotic Cells