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Article

Glutamyl-tRNAGln amidotransferase is essential for mammalian mitochondrial translation in vivo.

The Biochemical journal - 15 May 2014

Echevarría Lucía, Clemente Paula, Hernández-Sierra Rosana, Gallardo María Esther, Fernández-Moreno Miguel A, Garesse Rafael

Abstract excerpt

Translational accuracy depends on the correct formation of aminoacyl-tRNAs, which, in the majority of cases, are produced by specific aminoacyl-tRNA synthetases that ligate each amino acid to its cognate isoaceptor tRNA. Aminoacylation of tRNAGln, however, is performed by various mechanisms in different systems. Since no mitochondrial glutaminyl-tRNA synthetase has been identified to date in mammalian...

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PMID: 24579914
DOI: 10.1042/BJ20131107

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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