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Article

A single-nucleotide polymorphism tagging set for human drug metabolism and transport.

Nature genetics - 1 Jan 2005

Ahmadi Kourosh R, Weale Mike E, Xue Zhengyu Y, Soranzo Nicole, Yarnall David P, Briley James D, Maruyama Yuka, Kobayashi Mikiro, Wood Nicholas W, Spurr Nigel K, Burns Daniel K, Roses Allen D, Saunders Ann M, Goldstein David B

Abstract excerpt

Interindividual variability in drug response, ranging from no therapeutic benefit to life-threatening adverse reactions, is influenced by variation in genes that control the absorption, distribution, metabolism and excretion of drugs. We genotyped 904 single-nucleotide polymorphisms (SNPs) from 55 such genes in two population samples (European and Japanese) and identified a set of tagging SNPs that represents the...

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PMID: 15608640
DOI: 10.1038/ng1488

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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