Article
Single Nucleotide Polymorphisms as Genomic Markers for High-Throughput Pharmacogenomic Studies.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2016
Lonetti Annalisa, Fontana Maria Chiara, Martinelli Giovanni, Iacobucci Ilaria
Abstract excerpt
Genetic variations in patients have strong impact on their drug therapies and responses because the variations may contribute to the efficacy and/or produce undesirable side effects for any given drug. The Drug Metabolizing Enzymes and Transporters (DMET) assay is a high-throughput technology by Affymetrix that is able to simultaneously genotype variants in multiple genes involved in absorption, distribution,...
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