Article
[SNP collection, pharmacogenomics, and the future of drug therapy].
Gan to kagaku ryoho. Cancer & chemotherapy - 1 Sept 2002
Iida Aritoshi, Saito Susumu, Sekine Akihiro, Nakamura Yusuke
Abstract excerpt
Common genetic variations may, in large part, explain genetic predispositions to common diseases and individual differences in pharmacological responsiveness. Single-nucleotide polymorphisms (SNPs) are the most frequent type of genetic variation, and are thought to be present every several-hundred bases, on average, throughout the human genome. SNPs can provide medically important information through (1) their...
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