Article

Japanese Efforts in Pharmacogenomics.

2003-09-01

Abstract excerpt

A major goal of the Human Genome Project is to establish "personalized medicine" on the basis of individual genetic variations. Among the genetic differences present in human populations, polymorphisms in genes that encode various enzymes, transporters, and receptors involved in the metabolism of drugs are considered to be medically important because some can affect therapeutic efficacy of drugs and / or adverse r...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 0deda54e-e9b0-506a-b48c-ce6469efe798
DOI: 10.2174/1570160033476241

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Japanese Efforts in Pharmacogenomics.DOI 10.2174/1570160033476241Read

Japanese single nucleotide polymorphism database for 267 possible drug-related genes.Semantic proximity Read

Gene-based SNP discovery as part of the Japanese Millennium Genome Project: identification of 190,562 genetic variations in the human genome. Single-nucleotide polymorphism.Semantic proximity Read

[SNP collection, pharmacogenomics, and the future of drug therapy].Semantic proximity Read

A single-nucleotide polymorphism tagging set for human drug metabolism and transport.Semantic proximity Read

Catalog of 668 SNPs detected among 31 genes encoding potential drug targets on the cell surface.Semantic proximity Read

Role of single nucleotide polymorphisms in pharmacogenomics and their association with human diseases.Semantic proximity Read

Identification of 156 novel SNPs in 29 genes encoding G-protein coupled receptors.Semantic proximity Read

JSNP: a database of common gene variations in the Japanese population.Semantic proximity Read

Catalog of 680 variations among eight cytochrome p450 ( CYP) genes, nine esterase genes, and two other genes in the Japanese population.Semantic proximity Read

Catalog of 300 SNPs in 23 genes encoding G-protein coupled receptors.Semantic proximity Read

[Clinical pharmacogenetics and future prospects in drug therapy].Semantic proximity Read

Catalog of 320 single nucleotide polymorphisms (SNPs) in 20 quinone oxidoreductase and sulfotransferase genes.Semantic proximity Read