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Molecular heterogeneity and prognostic biomarkers in adults with acute myeloid leukemia and normal cytogenetics

15 Dec 2004

Abstract excerpt

PURPOSE OF REVIEW: Patients with acute myeloid leukemia (AML) and normal karyotype constitute the single largest cytogenetic group of AML, estimated to account for 45% of adults with de novo AML. This article critically reviews the recent literature that addresses the molecular heterogeneity of this group of patients and how this relates to prognostic stratification and novel therapeutic approaches. RECENT...

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PMID: 15604894
DOI: 10.1097/01.moh.0000149608.29685.d1

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